have or Consider you've got a genetic liver difficulty attributable to a mitochondrial condition such as Alpers-Huttenlocher syndrome.
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If a dose is skipped it should be taken right away, Except it is nearly time for the following dose. If a dose is skipped, the affected person must not double another dose.
are allergic to divalproex sodium, valproic acid, sodium valproate, or any on the components in Depakote. See the end of the Medication Information for a complete listing of elements in Depakote. Possess a genetic issue called a urea cycle ailment.
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seven.2 Effects of Valproate on Other Drugs Valproate has actually been located to become a weak inhibitor of some P450 isozymes, epoxide hydrase, and glucuronosyltransferases. The following listing gives specifics of the likely for an influence of valproate co-administration on the pharmacokinetics or pharmacodynamics of many generally prescribed prescription drugs. The checklist is not really exhaustive, considering that new interactions are continuously staying noted.
have or think you do have a genetic liver trouble brought on by a mitochondrial problem for instance Alpers-Huttenlocher syndrome.
These highlights usually do not include things like all the information needed to use Depakote securely click here and proficiently. See full prescribing info for Depakote.
1 Headache was the only adverse response that occurred in ≥ five% of sufferers while in the substantial dose group and at an equal or greater incidence in the low dose team.
have or think there is a genetic liver dilemma attributable to a mitochondrial disorder which include Alpers-Huttenlocher syndrome.
low overall body temperature (hypothermia). A drop in The body temperature to less than ninety five°F can materialize for the duration of remedy with DEPAKOTE. Call your Health care supplier if you have any of the next signs and symptoms:
Making use of DEPAKOTE with other medicines could cause critical Uncomfortable side effects. Will not start out or halt other medicines devoid of conversing with your Health care supplier. Specifically inform your healthcare service provider if you're taking:
are having it to prevent migraine head aches and therefore are both Expecting or may well come to be Expecting because you aren't making use of powerful start Management (contraception).